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Correction of benign intracranial hypertension syndrome when performing carotid endarterectomy by pharmacological improving of venous drainage to prevent cerebral hyperperfusion syndrome
Y.V. Rodin, D.S. Diuba, N.V. Yasnopolska, R.Y. Yusupov
Venous and liquor components of intracranial pressure (IP) in patients with benign intracranial hypertension syndrome (BIHS) when performing carotid endarterectomy were studied. Venous outflow from the cranial cavity was examined with sonography in two-dimensional and Doppler modes. Pharmacological correction of venous tone in patients with signs of increased IP was performed with a combined drug Normoven (diosmin with hesperidin, Kyiv Vitamin Factory) 500 mg BD. The study involved 60 patients (median age 55 years) who were divided into 2 groups: 30 patients who did not receive venomotor drugs in preoperative period, 30 patients who received Normoven within 1 month before surgery. Rapid normalization of venous-liquor indicators was observed in patients receiving Normoven in addition to standard medical therapy. Application of venomotor drugs improves venous outflow from the cranial cavity by reducing venous and liquor components in patients with BIHS when performing carotid endarterectomy. It is reasonable to include venomotor drugs in complex treatment of patients with cerebral hyperperfusion syndrome.
Keywords: intracranial pressure, benign intracranial hypertension syndrome, carotid endarterectomy, diosmin with hesperidin, Normoven.