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Preparation registered in Ukraine
Kravchenko E. V., Varvus E.V. The Department of Obstetrics, Gynecology and Perinatology SHI of Ukraine "Bukovinian state medical University" City clinical medical institution "Clinical Maternity Hospital ¹2»
Prevention of coplications in the first trimester of gestation in pregnant women with low placentation
The goal of this work is to develop new methods of prevention pregnancy complications in early pregnancy abnormal with placement of the placenta.
Materials and methods
We examined 64 pregnant women with low placentation in the First trimester of gestation. 34 patients (main group) with the purpose of prophylaxis of complications of pregnancy in early gestation took gestogen Lutein 2 times a day 100 mg and venotonic Normalen 1 tablet 2 times a day for month. The control group consisted of 30 women, management of pregnancy have been carried out according to the order ¹417, the Ministry of Public Health of Ukraine.
The efficacy of treatment was assessed by clinical data, data comparison of the chorion volume and development of its vascular system in pregnant women of studied groups (with the use of specialized three-dimensional VOCAL program), as well as using dopplerometric studies of blood flow in spiral arteries.
The results and conclusions of the study
The proposed method of prophylaxis in pregnant women with low placentation in the First trimester of gestation contributes to the growth of the volume of the chorion, the intensity of blood flow in the parenchyma and a complete restructuring of the spiral arteries, which ensures adequate formation of the placental-uterine blood flow.
The need for prevention of pregnancy complications in First trimester with low placentation is also confirmed by the results of clinical trials – the frequency of threatened abortion and bleeding when applying gestagens venotonic funds and decreased respectively in 2 and 3 times.
Keywords: low placentation, the First trimester of gestation, prevention of complications.